Variation across published reference equations and asthma studies are evident in the literature. ERS/ATS consensus 1 recommends phase III slope (SnIII) data from three technically acceptable washouts are pooled for Scond and Sacin calculation, but not how to achieve this. This can be partitioned into convection-dependent, primarily reflecting conductive airways (Scond), and diffusion-convection-dependent components, primarily reflecting acinar airways (Sacin). ![]() ![]() ![]() Introduction/Aim: Multiple breath nitrogen washout (MBNW) measures ventilation heterogeneity in peripheral airways. ![]() TP 001 Methods for pooling multiple breath nitrogen washout data in asthma Alowiwi H 1, Urroz P 1 ,2, Tonga K 1 ,3,5, King G 1 ,3, Robinson P 1 ,4, Thamrin C 1 1Woolcock Institute of Medical Research, University of Sydney, Sydney, Australia, 2Respiratory Medicine, Campbelltown Hospital, Campbelltown NSW, Australia, Sydney, Australia, 3Department of Respiratory Medicine, Royal North Shore Hospital, St Leonards, NSW, Australia, Sydney, Australia, 4Respiratory Medicine, Children's Hospital at Westmead, Westmead NSW, Australia, Sydney, Australia, 5St Vincent's Clinical School, University of New South Wales, Sydney, NSW, Australia, Sydney, Australia
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